Publications

Laboratory for Immunology of Metastatic Ecosystems

Find Jan Remsik's publications on PubMed

2025
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Interferon-γ orchestrates leptomeningeal anti-tumour response - Remsik J, Tong X, Kunes RZ, Li MJ, Estrera R, Snyder J, Thomson C, Osman AM, Chabot K, Sener UT, Wilcox JA, Isakov D, Wang H, Bale TA, Chaligné R, Sun JC, Brown C, Pe'er D, Boire A - 2025 - Nature - PubMed

Autocrine CXCL1-CXCR2 Signaling Mediates Leptomeningeal Resistance to Radiation Therapy - Osman AM, Remsik J, Snyder J, Wijetunga NA, Manoranjan B, Nobre AR, Freret M, Guber D, Chabot K, Piedrafita-Ortiz S, Tong X, Wang H, Li MJ, Dunbar AJ, Levine RL, Yang JT, Boire A. - 2025 - bioRxiv - PubMed

The covariance environment defines cellular niches for spatial inference - Haviv D, Remsik J, Gatie M, Snopkowski C, Takizawa M, Pereira N, Bashkin J, Jovanovich S, Nawy T, Chaligne R, Boire A, Hadjantonakis AK, Pe'er D - 2025 - Nat Biotechnol - PubMed

2024
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The path to leptomeningeal metastasis - Remsik J, Boire AA - 2024 - Nature Reviews Cancer - PubMed

T cells standing at the gates of brain metastasis - Remsik J, Boire AA - 2024 - Immunity - PubMed

Leptomeningeal metastases from solid tumors: A Society for Neuro-Oncology and American Society of Clinical Oncology consensus review on clinical management and future directions - Wilcox JAn Chukwueke UN, Ahn MJ, Aizer AA, Bale TA, Brandsma D, Brastianos PK, Chang S, Daras M, Forsyth P, Garzia L, Glantz M, Glitza Oliva IC, Kumthekar P, Le Rhun E, Nagpal S, O'Brien B, Pentsova E, Lee EQ, Remsik J, Rudà R, Smalley I, Taylor MD, Weller M, Wefel J, Yang JT, Young RJ, Wen PY, Boire AA - 2024 - Neuro Oncology - PubMed

Retinoid X Receptor Signaling Mediates Cancer Cell Lipid Metabolism in the Leptomeninges - Tong X, Remsik J, Brook J, Petrova B, Xu L, Li MJ, Snyder J, Chabot K, Estrera R, Osei-Gyening I, Nobre AR, Wang H, Osman AM, Wong AYL, Sidharta M, Piedrafita-Ortiz S, Manoranjan B, Zhou T, Murali R, Hamard PJ, Koche R, He Y, Kanarek N, Boire A. - 2024 -  bioRxiv - PubMed

2023
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Leptomeningeal anti-tumor immunity follows unique signaling principles - Remsik J, Tong X, Kunes RZ, Li MJ, Osman A, Chabot K, Sener UT, Wilcox JA, Isakov D, Snyder J, Bale TA, Chaligné R, Pe'er D, Boire A. - 2023 - bioRxiv - PubMed

Breast-to-brain metastasis is exacerbated with chemotherapy through blood-cerebrospinal fluid barrier and induces Alzheimer's-like pathology - Saatian B, Deshpande K, Herrera R, Sedighi S, Eisenbarth R, Iyer M, Das D, Julian A, Martirosian V, Lowman A, LaViolette P, Remsik J, Boire A, Sankey E, Fecci PE, Shiroishi MS, Chow F, Hurth K, Neman J. - 2023 - J Neurosci Res - PubMed

 

2020
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Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis - Chi Y, Remsik J, Kiseliovas V, Derderian C, Sener U, Alghader M, Saadeh F, Nikishina K, Bale T, Iacobuzio-Donahue C, Thomas T, Pe'er D, Mazutis L, Boire A. - 2020 - Science - PubMed